Comparative Study Of Free Radical Scavenging Potential Of Selected Myanmar Medicinal Plants
Volume 2 - Issue 2, February 2018 Edition
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Author(s)
Mya Thida, Khin Mar Mya, Chan Myae Nyein, Khin Nyein Chan, War War Lwin
Keywords
antioxidant, radical scavenging activity, nitric oxide, super oxide
Abstract
The present investigation was to compare the effect of radical scavenging activity between the selected ethanol extracts of Phyllanthus maderaspatensis L., Croton oblongifolius Roxb and Cynodon dactylon Pers. The effective antioxidant activity of selected extracts on DPPH radical was showed in following orders: Phyllanthus maderaspatensis L.> Croton oblongifolius Roxb > Cynodon dactylon Pers with their IC50 values of 48µg/ml, 64µg/ml and116µg/ml respectively. Texted extracts were compared with the standard ascorbic acid and its IC50 value was 5.6µg/ml. For the scavenging effect of nitric oxide radical, Cynodon dactylon Pers showed the most effective with IC50 value of 5.2µg/ml than Croton oblongifolius Roxb and Phyllanthus maderaspatensis L. with their IC50 value were 44.1µg/ml and 61.9µg/ml respectively. Three tested extracts were less scavenging activity than the standard Gallic acid IC50 value of 3.58µg/ml. In the super oxide radical scavenging assay, Croton oblongifolius Roxb possessed the strongest scavenging activity with IC50 value of 15.5µg/ml comparing the standard Gallic acid IC50 of 1.79µg/ml. The IC50 value of Phyllanthus maderaspatensis L. and Cynodon dactylon Pers were 22.3µg/ml and 32.9µg/ml respectively. The radical inhibition (%) activity of tested extracted showed the concentration- dependent elevation with the smallest IC50 value. In this observation, each texted extracts possessed the antioxidant activity and each have the different radical scavenging effects.
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