Effects Of Feeding Graded Levels Of Crude Oil-Containing Diets On Liver And Kidney Functions In The Growing Pig
Volume 4 - Issue 5, May 2020 Edition
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Author(s)
Ntinya C. Johnson Joy A. Okejim , Annie, O. Amakiri
Keywords
Liver and Kidney Biomarkers, Crude Oil, Contamination and Pig.
Abstract
Effects of feeding graded levels of crude oil-containing diets were studied on liver enzymes: alanine amino transferase (ALT), aspartic amino transferase (AST) and alkaline phosphatase (ALP) as well as on kidney biomarkers: blood urea nitrogen (BUN) and creatinine in growing pigs. 24 pigs of average body weight (BW) of 9 ± 1.4 (Mean ± SD) kg were used in the study. Animals were randomly assigned to their individual experimental pens. There were 4 graded crude oil dietary treatments: 0g (control group), 10g, 15g and 20g of crude oil/kg of diet. There were 4 replications per dietary treatment. Animals were fed at 5% of their BW for 4 weeks. Blood samples were collected from all animal in all the four dietary treatment groups at the end and snap frozen. ALT serum levels of diets 1 and 2 were similar (P > 0.05) but significantly (P < 0.05) lower than those of diets 3 and 4 with diet 4 having the highest (P < 0.05) significant serum value of ALT. The trends of ALT were mimicked by AST and ALP, respectively. BUN serum levels of diets 1 and 2 were similar (P > 0.05) but significantly (P < 0.05) lower than those of diets 3 and 4 again with diet 4 showing the highest (P < 0.05) significant value. Creatinine mirrored BUN fashion. It was concluded that ingestion of 10g of crude oil/kg diet had no effect on the liver and kidney; however at 15g and above of crude oil/kg of diet the crude oil negatively affected the health of the liver and kidney based on increased sera levels of their biomarkers as yardsticks.
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