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International Journal of Advanced Research and Publications!

Clinical Predictor For Drug Response Among Idiopathic Epilepsy Patients In Sudan

Volume 4 - Issue 2, February 2020 Edition
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Author(s)
Rasha Elhassan, AbassharHussein, Abdalla Khwad, Alsadig Gasoum, Sawsan Aldeef, Mohammed Saad, Salma Elhassan, Sanna Abdulaziz, Ghada Elhassan
Keywords
Epilepsy, Predictor, Factor, Pharmacoresistance, Remission.
Abstract
Epilepsy is one of the common chronic neurological diseases. It spreads widely in Sudan interrupting patients, life and annoying their care givers. Antiepileptic drugs are the corner stone in the management of epilepsy. It carries a good outcome which may be enrolled by some clinical factors. These factors help in determine treatment modality. Aim of the study To identify the clinical prognostic factors of idiopathic epilepsy in Sudanese patients. Methods there were 99 patients with idiopathic epilepsy recruited from Sheikh Mohamod Kheer health centre, Omdurman, Khartoum state, Sudan; between August 2016 and February 2019. There demographic data, seizure characteristics, drugs, and concomitant conditions were recorded in dc-hoc forms. The data was analysed using excel and SPSS program to compare between good and bad outcome of patients regarding different prognostic factors, and determine the likelyhood ratio and significance by chi square test. Results over all response to treatment were good in 89%. This response was associated insignificantly with age group above 65 years, focal seizure, duration less than 5 years, or monotherapy while frequency of seizure pretreatment and good response to first regiment has significant statistical response. Conclusion There was good response to treatment especially if the seizure frequency pretreatment was low, and the patient respond well to the first treatment regimen..
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