Liver And Kidney Functions Of Growing Pigs Fed Graded Levels Of Crude Oil-Contaminated Diets
Volume 4 - Issue 3, March 2020 Edition
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Johnson, N. C., Joy A. Okejim, J. A., Amakiri, A. O.
Crude Oil-Contaminated Diets, kidney biomarkers, Liver biomarkers and Pig.
This study was designed to investigate the effects of ingesting graded levels of crude oil-contaminated diets on the liver and kidney functions of the growing pig using their biomarkers. 24 growing pigs weighing on average 8 Â± 1.1 (mean Â± SD) kg of body weight (BW) were acquired and used in the study. The pigs on arrival at the animal wing of the Rivers State University Teaching and Research Farm were randomly assigned to six dietary treatment groups of 4 pigs per treatment. Dietary treatment groups were as: 0g, 2g, 4g, 6g, 8g and 10g of crude oil/kg of diet, respectively. The experimental animals were fed at 5% of their BW and the experiment lasted for 28 d. Blood samples were collected from all treatment groups into EDTA treated tubes and immediately snaps frozen for later analyses of biomarkers for the liver: Alanine amino transferase (ALT), Aspartic amino transferase (AST) and Alkaline phosphatase (ALP) as well as for kidney biomarkers: blood urea nitrogen (BUN) and creatinine levels. There were no significant (P > 0.05) differences in all the liver biomarkers measured, ALT, AST and ALP. Similarly, there were no significant (P > 0.05) differences in the two biomarkers of the kidney measured, BUN and creatinine contents for all dietary treatment groups. It was therefore concluded that crude oil contaminations up to 10g/kg of diet did not affect the liver and kidney of growing pigs, since their functions were not impeded.
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