Effects Of Feeding Graded Levels Of Crude Oil-Containing Diets On Antioxidants And Oxidants Statuses In Pigs
Volume 4 - Issue 3, March 2020 Edition
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Author(s)
Johnson, N. C., Okejim, J. A., Amakiri, A. O.
Keywords
Antioxidants, Contamination, Crude Oil, Oxidants and Pig
Abstract
Effects of graded levels of crude oil-containing diets were studied on sera levels of antioxidant enzymes: glutathione (GSH), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px) and oxidant malondialdehyde (MDA) in growing pigs. 24 growing pigs of average body weight (BW) of 9 ± 1.4 (Mean ± SD) kg were used in the study. Animals were randomly assigned to their individual pens. 4 graded crude oil dietary treatments: 0g (control group), 10g, 15g and 20g of crude oil/kg of diet were used with 4 replications per dietary treatment. Animals were fed at 5% of their BW for 4 weeks. GSH sera contents of animals on diets 1 and 2 were similar (P > 0.05) as there were no differences between them but significantly (P < 0.05) higher than those of animals in treatments 3 and 4 with group 4 animals demonstrating the lowest content. SOD contents of treatments 1 and 2 were similar (P > 0.05) and significantly (P < 0.05) higher than those of treatments 3 and 4 with diet 4 showing the lowest level. CAT sera contents of animals on treatments 1 and 2 were similar (P > 0.05) and significantly (P < 0.05) higher than those of treatments 3 and 4 with animals on diet 4 showing the lowest levels. For GSH-Px, there were no differences amongst groups. MDA sera contents of the animals on treatments 1 and 2 were similar (P > 0.05) but significantly (P < 0.05) lower than those of treatments 3 and 4 with treatment 4 showing the highest level. It was concluded that ingestion of 10g crude oil/kg diet had no effect on antioxidant enzymes; however at 15g and above antioxidants were suppressed while MDA levels increased. Beyond the 10g/kg of diet the health of animal was compromised as judged by lowered levels of antioxidants and increased MDA levels.
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