SJIF(2020): 5.702

International Journal of Advanced Research and Publications

High Quality Publications & World Wide Indexing!

Ethnobotanical Survey Of Plant Species Used In Traditional Medicine In Bekaraoka Region, Northeastern Madagascar

Volume 4 - Issue 3, March 2020 Edition
[Download Full Paper]

Micheline Marie Ange Tida, Olinirina Nanjarisoa , Jeanneney Rabearivony, Hery Lisy Tiana Ranarijaona , Taratra Andrée Fenoradosoa.
Bekaraoka, Ethnobotany, Madagascar, Northeast
Madagascar has one of the highest rates of biodiversity and endemism in the world, but the ethnobotanical reputation of Malagasy flora is still mediocre investigation. This article presents a preliminary study on the use of plants carried out in the village of Bekaraoka located in the North East of Madagascar. With the help of standardized questionnaires, two traditional healers and 175 informants were interviewed on the medicinal use of local flora. 76 species turned out to be used as a medicine by residents the area. Fabaceae Family predominates in number of species. Leaves were most commonly used, with 30,1 % of the plants being used to treat gastrointestinal disorders (diarrhea, abdominal pain, stomach aches). This paper provides new information on medicinal plants from one area of North East Madagascar never investigated for ethnomedicine and may be used as data base and information source for researchers who follow the ethnopharmacology approach.
[1] L. Gautier, S.M Goodman. Introduction to the flora of Madagascar. In The natural history of Madagascar. S. Goodman, J.P. Benstead (eds). pp. 229-250, 2003.

[2] J.G. Robinson. An island of evolutionary exuberance, Science, Vol. 304, pp. 53, 2004.

[3] M. Razafindraibe, A.R. Kuhlman, H. Rabarison, V. Rakotoarimanana, C. Rajeriarison, N. Rakotoarivelo, T. Randrianarivony, F. Rakotoarivony, R. Ludovic, A. Randrianasolo and R.W. Bussmann, Medicinal plants used by women from Agnalazaha littoral forest (Southeastern Madagascar), J. Ethnobiol. Ethnomed, vol. 9, pp. 73, 2013.

[4] J. Busch, R. Dave, L. Hannah, A. Cameron, A. Rasolohery, P. Roehrdanz and G. Schatz, Climate change and the cost of conserving species in Madagascar, Conserv. Biol, vol. 26, no. 3, pp. 408-19, 2012.

[5] S. Aubert, S. Razafiarison, A. Bertrand, Déforestation et systèmes agraires à Madagascar : Les dynamiques des tavy sur la côte orientale, Montpellier, CIRAD, 2003.

[6] C. Grimes, Le traitement de la lèpre par l'Hydrocotyle asiatica, Bulletin de la Société de pathologie exotique, vol. 6, pp. 692, 1939.

[7] Lasnet, Notes sur la pharmacopée des Sakalava du nord-ouest de Madagascar, Annales d'Hygiène de Médecine Coloniales, vol. 6, pp. 17-44, 1900a.

[8] Lasnet, Revue de Culture Coloniale, vol. 6, pp 171-175 (20 Mars), pp 209-213 (5 Avril), pp 233-238 (20 Avril), 1900b.

[9] G. Ramisray, La médecine des Malgaches, Revue de Madagascar, vol. 3, pp. 549-555, 190l.

[10] A. Dandouau, Ody et Fanafody, Bulletin de l'Académie Malgache,Vol. 11, pp 153–226, 1913.

[11] P. Boiteau, Introduction à l'étude des plantes fébrifuges de la flore malgache, Bulletin de la Société de Pathologie Exotique, vol. 30, pp 739-741. 1937.

[12] P. Boiteau, K. Sépacer, Rarimampianina and A. Rakoto-Ratsimamanga, Notes d'Ethnobotaniques Malgaches, Journal d'Applications Agriculturales et Botaniques Tropicale, vol. 15, no. 9-11, pp. 337-349, 1968.

[13] R. N. Rabesandratana, Résultats d'enquêtes et de localisations de plantes médicinales de la région de Toliara, Annales de I'Université de Madagascar, vol. 13, pp 131-150, 1978.

[14] N. Quansah, Ethnomedicine in the Maroantsetra Région of Madagascar, Economic Botany, vol. 42, pp. 370-375, 1988.

[15] S. Ratsimamanga-Urverg, P. Rasoanaivo, J. Le Bras, L. Ramiaramanana, A. Rakoto-Ratsimamanga and J.P. Coulaud, In vitro antimalarial activity and cytotoxicity of Srychnos mostuoides, Avicennia marina and Urophyllum lyallii, Discovery and Innovation, vol. 3, pp. 81-83, 1991a.

[16] S. Ratsimamanga-Urverg, P. Rasoanaivo, J. Le Bras, A. Rakoto-Ratsimamanga, O. Ramiliarisoa and J. Savel, Antimalarial activity and cytotoxicity of Fieus pyriJblia and Rhus (Baronia) taratana leaf extracts, Phytotherapy Research, vol. 5, pp. 32-34; 1991b.

[17] S. Ratsimamanga-Urverg, P. Rasoanaivo, J. Le Bras, A. Rakoto-Ratsimamanga, O. Ramiliarisoa, J. Savel and J.P. Coulaud, Antimalarial activity and cytotoxic- ity of Evodia fatraina stem bark extract, Journal of Ethnopharmacology, vol. 33, pp. 231-236, 1991c.

[18] P. Boiteau and M. Chanez, Isolement d’un nouvel acide triterpénique de Centella asiatica L. (Urb). de Madagascar : l’acide madecassique, CR Acad. Sci. Paris, vol. 264, no. 2, pp. 407-410, 1967.

[19] P. Rasoanaivo, D. Ramanitrahasimbola, H. Rafatro, D. Rakotondramanana, B. Robijaona, A. Rakotozafy, S. Ratsimamanga, M. Laibaied, P. Grellier, L. Allorge, L. Mambu, F. Frappier, Screening extracts of Madagascar plants in search of antplasmodial compounds, Phytotherapy Reasearch, vol. 18, pp. 742-747, 2004.

[20] J.B. Hudson, M.K. Lee, P. Rasoanaivo, Antiviral activities in plants endemic to Madagascar, Pharmaceutical Biology, vol. 38, pp. 36-39, 2000.

[21] C. Rivière, J.P. Nicolas, M.L. Caradec, O. Désiré and A. Schmitt, Les plantes médicinales de la Région Nord de Madagascar : une approche ethnopharmacologique, Bulletin de la Société Française d’Ethnopharmacologie et de la Société Européenne d’Ethnopharmacologie, vol. 36, pp. 36-49, 2005.

[22] M. Wink, Evolution of secondary metabolites in legumes (FABACEAE), South African Journal of Botany, vol. 89, pp. 164-175, 2013.

[23] U. Maloueki, J. Kapetshi, N.O. Kabena, K.S.P. Ndimbo, K.N.J.P. Ngbolua, N.B. Mbomba, C.D.M. Muganza, Activités antimicrobiennes et antioxydantes des extraits aqueux totaux des fruits de Dialium corbisieri et Dialium gossweilerii (FABACEAE-CAESALPINIOIDEAE), consommés par les bonobos, Bolobo, République Démocratique du Congo, Int. J. Biol. Chem. Sci, vol. 9, no 2, pp. 633-642, 2015.

[24] D.S. Seigler, Plant Secondary Metabolism, Boston, Dordrecht, London, Kluwer Academic Publishers, pp. 466-469, 1998.

[25] S.W. Pelletier, Alkaloids: chemical and biological perspectives, Amsterdam-Lausanne-New York-Oxford-Shannon-Singapore-Tokyo, Springer, pp. 10, 1996.

[26] G.A. Trease, W.C. Evans, Pharmacognosy, Avon, Great Britain, Bath Press, 14th Edition, 1991.

[27] A.A.L. Gunatilaka, Triterpenoids and steroids of Sri Lanka plants: a review of occurrence and chemistry, J. Natl. Sci. Ctry. Sri Lanka, vol. 14, no.1, pp. 1-54, 1986.

[28] R.R. Paris and H. Moyse, Précis de matière médicale, pharmacognosie spéciale dicotylédones (tome III), pp. 32-52, 1971.

[29] O. Spring, Chemotaxonomy based on metabolites from glandular trichomes, Botanical Research, vol. 31, pp. 153-174, 2000.

[30] F.B. Da Costa, L. Terfloth, J. Gasteiger, Sesquiterpene lactone-based classification of three ASTERACEAE tribes: a study based on self-organizing neural networks applied to chemosystematics, Phytochemistry, vol. 66, no. 3, pp. 345-353, 2005.

[31] L.M. Calabria, V.P. Emerenciano, M.T. Scott and T.J. Mabry, Secondary chemistry of COMPOSITAE, In: Systematics, Evolution, and Bibliography of COMPOSITAE (Funk VA, Sussana A, Stussey TF and Bayer RJ eds.), International Association of Plant Taxonomy (IAP-T), Vienna, Austria, pp 73-88, 2009.

[32] L.C. Keles, N. Isabel de Melo, Gabriela de P. Aguiar K.A.L. Wakabayashi, C. Eduardo de Carvalho, W.R. Cunha, A.E.M. Crotti, J.L.C. Lopes, N.P. Lopes, LYCHNOPHORINAE (ASTERACEAE) : a survey of its chemical constituents and biological activities, Química Nova, vol. 33, no10, pp. 2245-2260, 2010.

[33] Y. Yaoita, M. Kikuchi, K. Machida, Terpenoids and related compounds from plants of the family COMPOSITAE (ASTERACEAE), Nat. Prod. Commun., vol. 7, no. 4, pp. 533-538, 2012.

[34] S.S. Raymond, S.J. Jonathan, J.M. Watkins-Pitchford, The essence of analgesia and analgesics, Cambridge University Press, Cambridge, pp. 82-90, 2010.

[35] P. Russo, A. Frustaci, B.A. Del, M. Fini, A. Cesario, Multitarger drugs of plants origin acting on Alzheimer’s disease, Curr. Med. Chem, vol. 20, no. 13, pp. 1686-1693, 2013.

[36] P. Kittakoop, C. Mahidol, S. Ruchirawat, Alkaloids as important scaffolds in therapeutic drugs for the treatments of cancer, tuberculosis, and smoking cessation, Curr Top Med. Chem, vol. 14, no. 2, pp. 239-252, 2014.

[37] S. Qiu, H. Sun, A.H. Zhang, H.Y. Xu, G.L. Yan, Y. Han, X.J. Wang, Natural alkaloids: basic aspects, biological roles, and future perspectives, Chin J. Nat. Med, vol. 12, no. 6, pp. 401-406, 2014.

[38] T.P. Cushnie, B. Cushnie, A.J. Lamb, Alkaloids: an overview of their antibacterial, antibiotic enhancing and antivurulence activities, Int. J. Antimicrob. Agents, vol. 44, no. 5, pp 377-386, 2014.

[39] D. Metodiewa, A. Kochman and S. Karolczak, Evidence for antiradical and antioxidant properties of four biologically active N, N, diethylaminoethyl ethers of flavanone oximes: a comparison with natural polyphenolic flavonoid (rutin) action, Biochem. Mol. Biol. Int., vol. 41, pp. 1067-1075, 1997.

[40] M. Burak and Y. Imen, Flavonoids and their antioxidant properties, Turkiye Klin Tip Bil Derg, vol. 19, pp. 296-304, 1999.

[41] C. Ovando, D. Hernandez, E. Hernandez, Chemical studies of anthocyanins: a review, Food Chem, vol. 113, pp. 859-871, 2009.

[42] Y. Lee, D. Yuk, J. Lee, Epigallocatechin-3-gallate prevents lipopolysaccharide-induced elevation of β-amyloid generation and memory deficiency, Brain Res., vol. 1250, pp. 164-174, 2009.

[43] P.B. Telefo, L.L. Lienou, M.D. Yemele, M.C. Lemfack, C. Mouokeu, C.S. Goka, S.R. Tagne and F.P. Moundipa, Ethnopharmacological survey of plants used for the treatment of female infertility in Baham, Cameroon, J. Ethnopharmacol., vol. 136, pp. 178-187, 2011.

[44] M. Giday, Z. Asfaw, and Z. Woldu, Medicinal plants of the Meinit ethnic group of Ethiopia: an ethnobotanical study, J. Ethnopharmacol., vol. 124, pp. 513-521, 2009.

[45] K. Batawila, Diversité, écologie et propriétés antifongiques des COMBRETACEAE du Togo, Acta. Botanica. Gallica., vol. 149, no. 4, pp. 515-516, 2002.

[46] S. Rehecho, I. Uriarte-Pueyo, J. Calvo, L.A. Vivas and M.I. Calvo, Ethnopharmacological survey of medicinal plants in Nor-Yauyos, a part of the Landscape Reserve Nor-Yauyos-Cochas, Peru, J.Ethnopharmacol, vol. 133, pp. 75-85, 2011.

[47] A. Sophie, N. Eherhart; La phytothérapie – se soigner par les plantes, Edition Groupe Eyrolles, (2003), Deuxième tirage (2006), 2003.

[48] J.L. Betti, and S.R. Mebere Yemefa, Contribution à la connaissance des produits forestiers non ligneux du parc de Kalamaloué, Extrême Nord Cameroun: les plantes alimentaires. International, Journal of Biological and chemical Sciences, vol. 5, no. 1, pp. 291-303, 2011.

[49] M. Abouri, A. El Mousadik, F. Msanda, H. Boubaker, S. Baha and K. Cherifi, An ethnobotanical survey of medicinal plants used in the Tata Province, Morocco, Int. J. Med. Plants. Res, vol. 1, no. 7, pp. 99-123, 2012.

[50] E.H. Gbekley, D.S. Karou, C. Gnoula, K. Agbodeka, K. Anani, T. Tchacondo, A. Agbonon, K. Batawila, J. Simpore, Étude ethnobotanique des plantes utilisées dans le traitement du diabète dans la médecine traditionnelle de la région Maritime du Togo, PAMJ, vol. 20, pp. 437, 2015.

[51] N.R. Farnsworth, O. Akerele, A.S. Bingel, D.D. Soejarto, Z. Guo, Medicinal plants in therapy, Bulletin of the World Health Organization, vol. 63, pp. 965-981, 1985.

[52] J. Kheraro, J.G. Adam, La pharmacopée sénégalaise traditionnelle, plantes médicinales et toxiques, Paris: Vigot et Frères (Ed.), pp. 1011, 1974.

[53] A. Kobayashi, M.I. Adenan, S. Kajiyama, H. Kanzaki, K. Kawazu, A cytotoxic principle of Tamarindus indica, di-n-butyl malate and the structure– activity relationship of its analogues. Zeitschrift fur Naturforschung, vol. 51, pp. 233-242, 1996.

[54] Y.K. Ang, W.C.M. Sia, H.E. Khoo, H.S. Yim, Antioxidant potential of Carica papaya peel and seed, Focusing on Modern Food Industr, vol. 1, no.1, pp. 11-16, 2012.

[55] E.K. Marfo, O.L. Oke, O.A. Afolabi, Chemical composition of papaya (Carica papaya) seeds, Food Chemistry, vol. 22, no. 4, pp. 259-266, 1986.

[56] A.V. Coria-Téllez, E. Montalvo-Gónzalez, E.M. Yahia, E.N. Obledo-Vázquez, Annona muricata: A comprehensive review on its traditional medicinal uses, phytochemicals, pharmacological activities, mechanisms of action and toxicity. Arabian Journal of Chemistry, vol. 11, no. 5, pp. 662-691, 2018.

[57] Z.F. Fu, Z.C. Tu, L. Zhang, H. Wang, Q.H. Wen, T. Huang, Antioxidant activities and polyphenols of sweet potato (Ipomoea batatas L.) leaves extracted with solvents of various polarities, Food Bioscience, vol. 15, pp. 11-18, 2016.

[58] G. Zengin, M. Locatelli, A. Stefanucci, G. Macedonio, E. Novellino, S. Mirzaie, S. Dvorácskó, S. Carradori, L. Brunetti, G. Orlando, L. Menghini, C. Ferrante, L. Recinella, A. Chiavaroli, L. Leporini. and A. Mollica, Chemical characterization, antioxidant properties, anti-inflammatory activity, and enzyme inhibition of Ipomoea batatas L. leaf extracts. International Journal of Food Properties, vol. 20, no. 2, pp. 1907-1919, 2017.

[59] R.S. Bhat and S. Al-daihan, Antimicrobial activity of Litchi chinensis and Nephelium lappaceum aqueous seed extracts against some pathogenic bacterial strains, Journal of King Saud University Science, vol. 26, pp. 79-82, 2014.