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SJIF(2020): 5.702

International Journal of Advanced Research and Publications

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Protocol For A Trial Of The Impact Of Intensive Case Management Approach In Adults HIV Positive

Volume 1 - Issue 1, July 2017 Edition
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Author(s)
Jacques Lukenze Tamuzi1, Jonathan Lukusa Tshimwanga2
Keywords

Abstract
Background: Among the global gap in HIV epidemic to achieve the 90–90–90 target in 2015 was 13.0 million people living with HIV were not virally suppressed (UNAIDS 2016). In fact, the viral load is the mirror of HIV disease progression. Achieving the last 90 target is challenging because an estimated 38% [35–41%] of people living with HIV worldwide are virally suppressed. Disruptions of viral suppression of those on treatment, due to lack of adherence or viral resistance, limit the potential gains of treatment. Adherence is the best predictor of treatment success among clients. Near-perfect adherence is needed for clients to achieve good results, such as decreasing viral loads in the bloodstream, and preventing HIV-related complications. Maximum adherence to ART in patients with HIV improves health outcomes and prevents drug resistance. This trial will use intensive case management approach to improve adherence in adults HIV-infected whose viral load is >=1000 copies/ml. Objectives: -To improve the viral load in adults HIV-infected with viral load equal or above 1000 copies/ml. -To enhance the adherence in HIV-infected in adults with viral load >= 1000 copies/ml. Methods: This is a trial assessing viral load before and after the intervention. Participants will be selected in Otavi Health Centre. We will assess database in Otavi Health Centre and adults HIV-infected whose viral load is equal or above 1000 copies/ml will be selected. Data will be captured and entered into EpiInfo, then after converted to Stata14 for validation and analysis. The statistical analyses will be based on comparing the baseline viral load to post intervention viral load. Knowing that the viral load is continuous data, paired t-test will be used. We will use STATA 14 to analyze data. Conclusion: this trial will highlight the importance of intensive case management approach in improving ARV adherence.
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